Aktuelle Publikationen

 

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Aktuelle Publikationen aus Klinik und Forschung (Auswahl)

der Medizinischen Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie (CBF)

Lymphome

  • Scherger, A.K., Al-Maarri, M., Maurer, H.C., (...), Wunderlich, F.T., Rose-John, S., Keller, U.: Activated gp130 signaling selectively targets B cell differentiation to induce mature lymphoma and plasmacytoma. JCI Insight. 2019;4
  • Hüllein, J., Słabicki, M., Rosolowski, M., (...) Keller, U., Huber, W., Zenz, T.: MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma. Cancer Res. 2019;79:3125-38.
  • Weber, J., de la Rosa, J., Grove, C.S., (...) Keller, U., Vassiliou, G.S., Cadiñanos, J., Bradley, A., Rad, R.: PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice. Nat Commun. 2019;10:1415.
  • von Hoff, L., Kärgel, E., Franke, V., (...) Akalin, A., Mathas, S., Scheidereit, C.: Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma. Blood. 2019;133:1489-94.
  • Edginton-White, B., Cauchy, P., Assi, S.A., (...) Mathas, S., Cockerill, P.N., Bonifer, C.: Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma. Leukemia. 2019;33:1463-74.
  • Storck, K., Brandstetter, M., Keller, U., Knopf, A.: Clinical presentation and characteristics of lymphoma in the head and neck region. Head Face Med. 2019;15(1):1.

Leukämien

  • Schroeder, M.P., Bastian, L., Eckert, C., (...) Serve, H., Neumann, M., Baldus, C.D.: Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Sci Rep. 2019;9:4188.
  • Bastian, L., Schroeder, M.P., Eckert, C., (...) Gökbuget, N., Neumann, M., Baldus, C.D.: PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia. Leukemia. 2019.
  • James, A.R., Schroeder, M.P., Neumann, M., (...) Serve, H., Akalin, A., Baldus, C.D.: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia. J Hematol Oncol. 2019;12:8.

Weitere hämato-onkologische Forschung

  • Maurer, S., Herhaus, P., Lippenmeyer, R., (...) Grigoleit, G.U., Keller, U., Lapa, C.: Side effects of CXC-chemokine receptor 4 - directed Endoradiotherapy with Pentixather prior to Hematopoietic Stem Cell Transplantation. J Nucl Med. 2019.
  • Nimmagadda, S.C., Frey, S., Müller, P., (...) Keller, U., Edelmann, B., Fischer, T.: SDF1α-induced chemotaxis of JAK2-V617F-positive cells is dependent on Bruton tyrosine kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA. Haematologica. 2019;104:e288-92.

Solide Tumore

  • Lux, M.P., Böhme, S., Hücherig, S., Jeratsch, U., Kürschner, N., Lüftner, D.: Surrogate threshold effect based on a meta-analysis for the predictive value of progression-free survival for overall survival in hormone receptor-positive, HER2-negative metastatic breast cancer. Breast Cancer Res Treat. 2019;176:495-506.
  • Busse, A., Lüftner, D.: What Does the Pipeline Promise about Upcoming Biosimilar Antibodies in Oncology? Breast Care (Basel). 2019;14:10-6.
  • Lüftner, D.: Approval by Authorities Does Not Allow For Suboptimal Study Conduct but Offers New Academic Possibilities. Breast Care (Basel). 2019;14:2-3.

Palliativmedizin

  • Preisler, M., Rohrmoser, A., Goerling, U., (...) Riemer, M., Heuse, S., Letsch, A.: Early palliative care for those who care: A qualitative exploration of cancer caregivers' information needs during hospital stays. Eur J Cancer Care (Engl). 2019;28:e12990.