
Projects of the Keller Group
Sie befinden sich hier:
Currently, the Keller Group focuses on the following research projects:
Myc-associated cancer biology

Functional genomic screening


Aberrant Ub/SUMO activity in cancer

Chemokine receptor signaling

Immuno-Oncology

SUMOi drives induction of the MHC-I/APM pathway in tumor cells and the activation of T cells. When both cell types are combined, SUMOi drives a feed-forward mechanism amplifying the antitumor immune response.